Consequences of poisoning (overdose) with phenazepam and treatment
Many drugs are prescribed by the doctor for a long time. But the patient does not always ask about the features of use, contraindications or incompatibility, and sometimes skips past this important information.
One of the drugs, the infamous resuscitator and drug treatment specialist - Fenazepam. Consuming it with alcohol can lead to serious poisoning with Phenazepam and even death. Consider all the consequences of poisoning with this medicine.
Phenazepam is widely used by doctors to treat insomnia, neurotic disorders, panic attacks, stresses and phobias, to relieve alcoholic and drug withdrawal symptoms (withdrawal syndrome, or "breaking"), as well as convulsive syndromes and preparing for general anesthesia during operations.
This medicine belongs to the psychotropic drugs of the benzodiazepine series. Stored on list B, that is, refers to potent substances. You can buy it only by prescription prescribed by a doctor.
Contraindications to the use of phenazepam
Phenazepam is not prescribed for myasthenia gravis, glaucoma, children and adolescents under 18 years of age, pregnant and lactating women, as well as for shock, coma and acute respiratory failure.
Phenazepam is used with caution in case of hepatic and renal failure, depression, organic brain damage, a tendency to abuse alcohol and psychotropic drugs. It is also not recommended to take Phenazepam to older people.
When does an overdose occur, can Fenazepam be poisoned? The drug is categorically incompatible with alcohol! Having a suppressive effect on mental processes and the activity of the central nervous system, the joint use of alcohol and Fenazepam causes sharp mental disturbances and basic life processes, including the cessation of breathing and death.
Symptoms of Phenazepam poisoning
Long-term use of Phenazepam is not recommended, since, among other things, addiction develops to the drug. With a long, over two weeks course of taking the medication should be particularly careful. Usually, doctors prescribe a course of treatment for a period of two weeks to two months. It should be borne in mind that long-term use of Phenazepam is addictive, it is required to increase the dose. Also, the drug causes addiction and withdrawal syndrome.
In acute poisoning with Phenazepam, the symptoms are as follows:
- decrease in all reflex functions;
- drowsiness - it is impossible to wake the patient;
- confusion of consciousness;
- muscle tremor;
- slow heart rate;
- shortness of breath, shortness of breath;
- lowering blood pressure;
- stupor and coma.
With prolonged use or overdose, the following side effects may occur:
- general weakness, drowsiness, depression;
- lack of coordination of movements;
- slowing mental and physical reactions;
- headaches, memory impairment, disorientation in space, confusion;
- feeling of euphoria or worsening of mood.
Phenazepam poisoning in children
Cases of acute poisoning with Phenazepam in children are quite common. This is due to both the accidental use of the drug prescribed to someone from home, and special use (suicide). According to statistics, such cases constitute about 20% of all acute poisonings with medical preparations in children.
The most frequently affected children are from one to three years old (about 60%) and of high school age from nine years old and up to fifteen - about 20% of cases.
Symptoms of the nervous system dysfunction prevail:
- lack of coordination;
In young children with Phenazepam poisoning, treatment is more favorable than in adolescents, which is associated with instability of cardiac activity in the latter.
First aid in case of poisoning with Phenazepam
In case of poisoning with Phenazepam, what to do first? Immediately call the ambulance brigade!
Further, the procedure should be as follows.
- If the victim is conscious, then induce vomiting. To do this, drink a large amount of liquid — a saturated solution of sodium or sodium sulfate in a volume of 1–1.5 liters, or plain water of 3–5 liters.
- Take activated carbon. Tablets better crushed and mix in a little water. Instead of coal, you can take other adsorbents: Enterosgel, Sorbeks, White coal.
- To monitor the patient's condition, if he loses consciousness, you need to ensure that the victim does not choke on vomit. To do this, turn it over to one side and pull the tongue out of his mouth. The tongue can be tied through a bandage to the handle of the cutlery (spoon).
The consequences of poisoning with Phenazepam can be very serious, so even if vomiting has occurred, consult a doctor. Medicines are very quickly absorbed from the stomach and to neutralize it in the blood requires the introduction of an antidote. If possible, take the patient to the emergency room of the hospital so that he will be given the necessary help more quickly.
In case of poisoning with Phenazepam, the lethal dose depends on many related factors: alcohol dose, mental state, heart, liver and kidney activity, the presence of chronic diseases, addiction to the drug. According to the instructions, the maximum permissible daily intake for oral administration is 0.01 grams.
The victim is given a gastric lavage and injected with a substance that neutralizes Phenazepam. Oriented to the general condition of the patient, the activity of the cardiovascular system and the nature of breathing. If necessary, conduct a blood test for serum phenazepam.
Flumazenil (Anexat) is used to treat overdose with drugs from the benzodiazepine group. He is an antagonist of Phenazepam and has a short action. A dropper is put in case of poisoning with Phenazepam or administered intravenously in a stream with glucose or saline at a dose of 0.2 mg of Anexata for 30 seconds, up to a total dose of 3-5 mg. Antidote is contraindicated in patients suffering from epilepsy in severe mixed poisoning with benzodiazepines and proconvulsants (Aminophylline, Amitriptyline).
Also used symptomatic means aimed at maintaining cardiovascular activity and respiration, drugs to stimulate the activity of the central nervous system.
Be careful in taking Fenazepam. Do not leave tablets in an accessible place, especially if there are young children at home. Do not use the drug without the recommendation of the attending physician. Remember, sharing Phenazepam and alcohol is unacceptable! In case of poisoning, induce vomiting and seek medical attention immediately.