Consequences of analgin overdose
Analgin is known for the ability to relieve pain, reduce body temperature. To a lesser extent, it reduces the inflammatory process. It is used in febrile conditions of various nature, moderate pain syndrome of nervous or muscular nature, with bile, urinary, intestinal colic in combination with other analgesics.
But is it possible to poison with analgin, and if it is possible, then how does it happen and how dangerous is it? How do I notice an overdose on time, and what do I do? Let's analyze these questions, and also learn what to do if you are poisoned with an analgin of a child.
Causes of analgin overdose
The main causes of analgin overdose are as follows.
- Abuse of analgesic tablets for chronic pain caused by any long-term illness.
- The use of analgin in the violation of the liver and kidneys.
- Joint intake of analgin and agents from the barbiturate group: Codeine, Anaprilin, antihistamine drugs - enhances its effect. Therefore, the use of even therapeutic doses can provoke intoxication.
How the analgin behaves in the body
Analgin is readily soluble in water, which contributes to its rapid absorption in the intestine. Therefore, the use of a large dose quickly creates a high concentration of the drug in the blood, which leads to an overdose. Its long-term use causes suppression of the formation of cells in the blood. The drug can provoke a narrowing of the lumen of the bronchi, therefore, people with bronchial asthma, chronic bronchitis accompanied by an exhalation violation, analgin is contraindicated. The presence of severe renal and hepatic insufficiency causes a slowdown in the cleavage and excretion of the drug from the blood, which leads to toxic effects and poisoning.
The maximum dose for one reception is 1 gram, per day - 3 grams. Enter intramuscularly or intravenously, not more than 2 grams per 24 hours. The average lethal dose of analgin is about 5 grams. For each person, it will be its own depending on the weight, the way of administration of analgin, the absorption capacity of the intestine and other factors.
Symptoms of analgin poisoning
When poisoning with analgin, the symptoms will differ slightly in case of acute and chronic course. Single consumption of a large dosage or prolonged abuse of tablets inflicts a major blow to the blood, liver, kidneys, vessels in some cases - light.
On the part of the blood there is a sharp decrease in the quantitative content of circulating cells: leukocytes, platelets. Leukocytes are responsible for immune processes. The first 3 days of their lack may not be manifested. Immunity keeps on the chain of microscopic inhabitants of the body. Reduction of leukocytes releases the flora to freedom, its activation takes place. It causes inflammation of the mucous membranes with the development of ulcers and necrosis of tissues. The mucous membrane of the oral cavity (stomatitis) is affected, angina arises, inflammation of the gums, ulcers in the stomach, intestines are formed. Foci of damage are formed in the trachea, bronchi, lungs. There is an inflammatory defeat of the urinary tract. Reduction of platelets leads to increased bleeding, in severe cases, bleeding develops.
Chronic poisoning with analgin causes gradual development of inflammatory processes. It all starts with long-lasting non-healing ulcers and wounds in the mouth, which can not be treated with pharyngitis, tracheitis, bronchitis. Prolonged poisoning in people with chronic lung diseases can provoke bronchial spasms, accompanied by a paroxysmal cough, shortness of breath while walking or at rest. From the side of the kidneys there will be a decrease in urination. In urinalysis in such patients, a cluster of bacteria is found, a protein. The poisoning effect on the liver is manifested by coloring the skin and mucous membranes in yellow, skin itching, accumulation of bilirubin in the blood. In addition, the following symptoms may appear:
- lowering blood pressure;
- abdominal pain;
- violation of consciousness, delirium;
- complete loss of consciousness, coma.
Is it possible to die from an overdose of analgin? You can, if you drink 5 to 8 grams of medicine. Death occurs more often from severe infectious complications, which occur atypical, difficult and difficult to treat. Less often, the cause of the lethal outcome of an analgin overdose is acute renal and hepatic insufficiency. You can die from hemorrhages to vital organs (brain, heart), paralysis of the respiratory center. That this does not happen, it is necessary to be engaged in treatment more likely. About it the speech is ahead.
First aid and treatment
The first help in poisoning with analgin is reduced to provoking vomiting, taking activated charcoal depending on the weight category of the victim. At a weight of 70 kg for 1 time you can safely drink 20 tablets of coal, with the normal tolerability of this sorbent. Also, you must take saline laxatives or make an enema. Seek medical attention if you are overdosed with analgin.
Such patients need careful monitoring, therefore, hospitalization is most likely to follow. In the hospital they will take the necessary tests, make a stomach wash.
One of the ways to treat poisoning with analgin is forced diuresis. It increases the leaching of the drug from the blood. If the kidneys are seriously affected, hemodialysis is prescribed. Infectious complications are treated with antibiotics of the latest generation or can use reserve antibacterial drugs, which are used only in extreme cases. Conducted anticonvulsant and other symptomatic treatment.
Consequences of analgin overdose
The consequences of analgin overdose depend on the duration and severity of the poisoning, the time of care, the presence of other diseases, the age of the victim. Most likely, the consequences of intoxication will be as follows:
- death from an analgesic overdose;
- impaired liver and kidney function;
- hemorrhage to the brain, heart, intestines, kidneys, liver, followed by a violation of their work, depending on the amount of damage;
- the formation of chronic infections with a strong suppression of immunity.
Features of poisoning analgin in children
An overdose of analgin in children occurs when the dose is incorrectly selected or the child ate the beautiful tablets. The maximum daily dose in children is 10 milligrams per kilogram of their weight.
Poisoning is often acute. Cases of chronic intoxication in children are rare. Symptoms are basically the same as in adults, however, events can develop very quickly. The younger the child, the faster the loss of consciousness and cramps.
First aid for child analgin analgesia
- Try to do everything quickly and calmly without unnecessary fuss.
- Take out the pill from the mouth, which the kid has not yet had time to eat.
- Call for an ambulance.
- A child under 5 years old will try to drink with a sorbent and give a warm liquid in small portions before the arrival of a doctor. You can give milk, it can slow the absorption of the medicine.
- If the child is over 5 years old, try to induce vomiting.
- Do not feed.
- Collect the necessary things in the hospital.
Any medicine can become a poison. Knowledge of the symptoms will help in time to notice the threat to health, and perhaps, life. The provision of first aid plays a major role in the rescue of a person, in the formation of immediate and remote consequences, and can also prevent a fatal outcome in an overdose of any medicine, including analgin.
It is necessary to keep medicines high, but better under lock and key to protect children. A child older should be explained that drugs can not even be touched without permission. The strict adherence to the prescriptions of the doctor and the cessation of self-treatment will save many lives.