The classic representative of antiallergic drugs - "Dimedrol". Many use it often as a sedative and hypnotic substance. All these effects are due to its inhibitory effect on the nervous system. But the uncontrolled intake of this drug is dangerous, it can lead to a negative effect on the brain and other vital systems in the human body.
Is it possible to overdose "Dimedrol" and what is it expressed in? What is the most dangerous consequence of careless use of this medicine? And, most importantly, how to cope with this, if you accidentally took too much of his dose?
What is "Dimedrol"
"Dimedrol" refers to the group of first-generation antihistamine drugs. It blocks histamine receptors (stimulating their work increases the tone of the smooth muscles of the intestines, bronchi and bladder) and inhibits the work of the nervous system, has an antiemetic activity to a small extent. Is it possible to get Dimedrol? - yes, he, like many other drugs, in large quantities can be dangerous.
"Dimedrol" is included in the list of essential medicines and is included in the list of drugs for emergency care. In pharmacies, it can be found in the form of tablets of 0.03-0.05 grams and solutions for intramuscular administration of 1% - 1 ml, in syringe tubes it is produced for use in diseases of the mucous membranes. For children, "Dimedrol" is produced in candles, and for skin diseases, a cream or ointment is made in a pharmacy. The course of treatment depends on the disease for which it is prescribed. In tablets, on average, prescribe the drug for 10-15 days, one three times a day.
Overdose "Dimedrol" - how many pills? The highest single dose is not more than 0.1 g, daily - 0.25 g. This is the maximum - five tablets per day. The drug begins to act after a few minutes, and the duration of its work - 12 hours.
When prescribed "diphenhydramine"
In which diseases is prescribed "Dimedrol" and what effects are observed from its reception?
- It is widely used as an antiallergic agent. It can be treated with urticaria, hay fever, hemorrhagic vasculitis and serum sickness. For quick relief of symptoms, injections are used. In this case, a single dose should be 5 ml. Overdose "Dimedrol" in ampoules occurs with the introduction in the course of the day more than 15 ml of the substance. A person has symptoms of poisoning.
In diseases of the ENT organs, they are used to reduce the inflammation of the tissues: for rhinitis, inflammation of the pharynx.
- Assign with blood transfusion and blood-substituting solutions to reduce the response of the body.
- Often in hospitals it is used in addition to the main treatment in order to enhance the effect of other drugs or for a sedative effect (as it inhibits the action of the nervous system).
- Due to the pronounced hypnotic function it is used before bedtime.
- "Dimedrol" relaxes muscles, so it is often prescribed for diseases of the gastrointestinal tract. In case of nausea and vomiting, pregnant women are rarely used, but not more than a single dose, in order to avoid Dimedrol poisoning.
Assign with sea and air sickness.
- In ophthalmology use drops with iridocyclitis and conjunctivitis. Consequences of overdose Dimedrol drops can come instantly - it is dry and itchy mucous membranes.
- As well as other antihistamines, it is used for radiation sickness.
"Dimedrol" is widely used in almost every field of medicine. But despite this, the drug is prescribed only by prescription for which there is a good reason. It brings not only benefits, - in case of overdose or misuse, diphenhydramine is harmful and can lead to health problems.
Overdose "Dimedrol" tablets and solution threatens with major troubles. The clinical picture is determined by the amount of the substance taken.
- "Dimedrol" is quickly absorbed, in case of accidental contact of the solution with the skin or mucous membranes, possibly numbness of the place of contact.
- Ingestion of 1–2 g of substance may cause dizziness, headaches, nausea, dry mouth, signs of stunning, muscle weakness, double vision, and tremor (trembling) of the hands.
- Overdose will lead to depression of the central nervous system. After taking a large dose (3-5 grams) delirium develops with signs of fear, fearfulness, incoherent speech. In small doses, drowsiness and severe general weakness will be observed.
- Diphenhydramine does not affect blood pressure, but in case of severe blood loss, it can drastically reduce it.
You can not simultaneously apply "Dimedrol" with alcoholic beverages. Their joint use will lead to the appearance of hallucinations. In this case, even a small dose of “Dimedrol” can be fatal to humans.
- Caution is prescribed in case of diseases of the respiratory system - in addition to dry mucous membranes, thickening of sputum and a short-term deterioration are observed.
- "Diphenhydramine" affects the heart: leads to the appearance of heart palpitations and rhythm disturbances, the emergence of extrasystoles - extraordinary contractions of the heart muscle.
- Symptoms of Dimedrol overdose for skin diseases: rash in the form of urticaria, itching and photosensitivity.
- Prolonged uncontrolled use of "Dimedrol" can lead to irreparable changes in the blood - hemolytic anemia, reduction in platelet count, agranulocytosis.
- Rarely, urinary impairment and swelling of the extremities may occur.
Proper administration, compliance with safety rules and the prescribed dose will not lead to such often irreparable complications.
Symptoms of poisoning
“Dimedrol” is often taken for a long time, while confidence in the anesthetic, soothing effect of taking this drug has time to gain a foothold in the mind of a person. Because of this, they often start taking the drug in large doses, increasing the frequency of intake. Overdose symptoms of poisoning will be as follows:
xerostomia (dry mouth), thirst;
- dizziness, nausea;
- muscle twitching;
- motor and mental excitement, impaired consciousness, hallucinations;
- convulsions, followed by loss of consciousness, coma;
- a sharp drop in blood pressure;
- respiratory depression.
There is no specific antidote "Dimedrol". Emergency care is to flush the stomach. The victim should be given a saline laxative, activated charcoal at least 8 tablets at a time.
If a person takes 5 or more grams of Dimedrol at the same time, a coma of 5–6 hours may occur. In this case, he is immediately taken to the hospital, tracheal intubation is performed, and artificial ventilation of the lungs is provided.
Health workers know that overdose of Dimedrol can be fatal. Therefore, the substance is prescribed only if there are indications for its reception and in small quantities.
"Dimedrol" is very popular in medical practice, but its side effects are often incomparable with the possible consequences. Therefore, it is better to abandon the independent use of this medication, once again to be safe and consult with your doctor.