Overdose of Vitamin E
Many vitamins belong to the group of substances that can not be fully used as medicines. But without these irreplaceable compounds, the human body is prone to the development of diseases of virtually all systems and organs. One capsule containing in its composition a full complex of vitamins, often serves as the prevention of acute illnesses.
The benefits of taking such substances are obvious, if not a small fly-fly. These compounds belong to the group of fat-soluble vitamins, which in excess can lead to bad consequences. Can an overdose of vitamin E occur? Yes, it can be, but how to avoid it and what if it happened?
What is Vitamin E
Vitamin E (tocopherol) refers to fat-soluble compounds. These are the chemicals that are not synthesized in the human body, and their natural sources are better absorbed if there are lipids (fats) in food. The main way of getting into the human body is with food. But it is not always possible to fully balance your daily diet so that all useful micronutrients are in abundance for the necessary vital processes. Therefore, often doctors prescribe vitamin E in the form of capsules or injections. Without him anywhere, many important and irreplaceable reactions in our cells pass only with his participation.
- It promotes the full absorption of vitamin A, while increasing its activity.
- Maintains normal cell structure, protecting their membranes (membranes).
- It is an active antioxidant.
- Protects the body from hypoxia, affecting cellular respiration.
- Participates in the formation of heme, many proteins, hormones and the development of the placenta.
Therefore, it is recommended to prescribe vitamin E during pregnancy, with the onset of acute infectious diseases, small children. The daily dose of vitamin E varies according to the indications.
Indications for use of vitamin E
Preparations containing vitamin E are prescribed for many diseases and temporary physiological conditions. In medicine, there is no area in which tocopherols would not be used.
- With degenerative changes in skeletal muscles, heart, hypotrophy (disruption of development and nutrition of these systems, which leads to a weakening of their functions).
- In neurology in violation of gait.
- Gynecologists appoint during pregnancy and at risk of spontaneous abortions.
- Used if the permeability and fragility of capillaries is increased.
- Dermatologists actively recommend a remedy for dermatoses and psoriasis.
- Applied with liver disease, a violation of potency.
The daily norm of vitamin E for children of different years of life can be from 3 to 15 mg, depending on the age. In an adult healthy person, this figure is 15 mg. Pregnant women should take a large daily dose of vitamin 20 mg. Some sources have data in the ME (metabolic units), 20 mg corresponds to 30 IU. With many diseases of the nervous and muscular system, 100 to 300 mg of tocopherol is prescribed per day.
To ensure the daily requirement of the body for such a substance, it is necessary to add foods in the diet in which there is vitamin E:
- peas, beans;
- vegetable oils (sunflower, peanut, sea-buckthorn);
- young sprouts of cereals - sprouted wheat;
- meat, eggs and milk.
Normally, with food, it does not always come in enough, so an overabundance of vitamin E can happen only when using synthetic drugs.
Even a double dose of drugs containing vitamin E will not cause an unusual reaction of the body. More often, its excess and poisoning occurs when intramuscular injection of large doses. If you receive one dose of vitamin E at a time, the following symptoms of an overdose will appear.
The most frequent undesirable effect is an allergic reaction. It can be in the form of urticaria or a local edema when the drug is administered intramuscularly.
- In pediatrics it is used for vitamin D hypervitaminosis. Incorrect or excessive administration of drugs containing tocopherol in complex treatment will subsequently lead to a decrease in the level of calcium.
- In large quantities, the substance affects the blood cells, reducing the number of platelets and white blood cells. This symptom can be observed with an overdose of vitamin E in a child. Another formidable complication is sepsis (blood poisoning) if the drug is used in premature infants.
- Excess inhibits the work of liver cells and kidneys, which can be noticeable not immediately. A person is worried about weakness, a sharp decline in efficiency. Therefore, with the long-term use of tocopherols for medical purposes, it is recommended that you regularly take a biochemical blood test for monitoring.
- Intramuscular administration can also lead to some complications: the appearance of redness or the development of calcifications at the site of administration.
- Symptoms of vitamin E overdose include diseases of the digestive system: enterocolitis (inflammatory process in the small and large intestine), enlargement of the liver, appearance of fluid in the abdominal cavity (ascites).
- Excess amount of the drug affects the integrity of the vascular wall, so there may be bleeding in the retina of the eye, in severe cases in the brain.
- Tocopherol raises blood pressure.
Correction of excess vitamin E
This happens rarely, because usually they treat a deficiency of tocopherol. Hypervitaminosis of vitamin E occurs after its introduction intramuscularly or with the occasional use of the substance more than the prescribed dose. How to treat this condition?
- Cancellation of the drug.
- There is no specific antidote, therefore, symptomatic therapy is prescribed: intravenous injection of plasma-substituting solutions, lowering the level of pressure, hepatoprotectors protecting liver cells are appointed.
- In severe situations, a person is hospitalized in the intensive care unit.
Overdose of vitamin E in pregnancy, in childhood and in sick people happens most often through negligence. To prevent this from happening, it is necessary to be attentive, to select drugs after consultation with a doctor and having completed a complete examination. The appearance of the first signs of poisoning with tocopherol is an indication for contacting a polyclinic at the place of residence or in a hospital.